Our Abpromise guarantee covers the use of ab11798 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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IHC-P
IHC-P: Use a concentrati...Read more →
IHC-P: Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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WB
WB: Use a concentration ...Read more →
WB: Use a concentration of 0.1 - 0.5 µg/ml. Detects a band of approximately 34 kDa.
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ICC/IF
ICC/IF: Use at an assay ...Read more →
ICC/IF: Use at an assay dependent concentration. PubMed: 22021442
Target
Function
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Sequence similarities
Belongs to the ARPC2 family.
Cellular localization
Cytoplasm > cytoskeleton. Cell projection.
Target information above from: UniProt accessionO15144The UniProt Consortium The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Information by UniProt
Alternative names
Actin related protein 2/3 complex subunit 2 34kDa antibody
Actin related protein 2/3 complex subunit 2 antibody
Actin-related protein 2/3 complex subunit 2 antibody
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