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现在位置首页>实验室原料试剂耗材>干细胞>干细胞试剂盒>bpsbioscience,50272,BCL-2, His-tag
bpsbioscience,50272,BCL-2, His-tag
bpsbioscience,50272,BCL-2, His-tag
  • bpsbioscience,50272,BCL-2, His-tag

bpsbioscience,50272,BCL-2, His-tag

产品报价:询价

更新时间:2019/2/19 16:35:28

地:美国

牌:bpsbioscience

号:50272

厂商性质: 生产型,贸易型,服务型,

公司名称: 世联博研(北京)科技有限公司

产品关键词: SARM1 FLAG-Tag   Caspase6 His-tag   BCL-XL   His-tag  

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程园 : (18611717737) (010-57129142)

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Species: Human
Host Species: E. coli
MW: 27 kDa
Genbank #: P10415
Tag(s): C-terminal His-tag
a.a: 1–211
Background:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Description:
Human Bcl-2 (GenBank Accession No. P10415), a.a. 1-211 with C-terminal His-tag, MW = 27 kDa, expressed in an E. coli expression system.
UniProt
P10415
Synonym(s):
Bcl, Bcl2, B cell lymphoma 2
Assay Conditions:
Following the protocol for BPS Cat. #50222. Briefly, BCL-2 was combined with BCL-2 peptide ligand in TR-FRET assay buffer along with anti-His Tb donor and dyelabeled acceptor. Varying concentrations of ABT 199 were added and the reaction was incubated at room temperature for 2 hours followed by fluorescent intensity measurements.
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Format:
Aqueous buffer solution
Application(s):
Useful for the study of apoptosis, screening inhibitors, and selectivity profiling.
Reference(s):
1. Labi V. et al., Cell Death Differ. 2008 Jun;15(6):977-87.
2. Rong Y.P. et al., Mol Cell. 2008 Jul 25;31(2):255-65.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Apoptosis
Product Type:
Recombinant Protein

 

 

 

目录#尺寸产品名称
50272100微克BCL-2,His-tag
50273100微克BCL-XL,His-tag
100077100微克BCL2A1,His-Tag
100080100微克BCL2L10,His-Tag
100091100微克BCL2L2,His-Tag
80500

10微克
50微克

Caspase3,His-tag
80113

10微克
50微克

Caspase6,His-tag
70000

10微克
50微克

Caspase7,His-tag
80114

10微克
50微克

 

Caspase8,His-tag
8011550微克Caspase9,His-tag
40742100微克MCL1,His-Tag
801175微克NLRP3(NALP3),His-FLAG标签(Sf9衍生)
100069100微克SARM1,FLAG-Tag
7500320微克STAT3,GST-tag
8001650微克WDR5,His-Tag,Biotin-Labeled
7500250微克XIAP(Bir2,Bir3),His-tag
7500150微克XIAP(Bir3),His-tag
8040120微克XIAP,FLAG-tag

世联博研(北京)科技有限公司

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手机:18611717737

联系人:程园

电话:010-57129142

传真:010-57129142

QQ:631767688

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