产品报价：300元
更新时间：2013/10/29 14:33:21
产地：美国
品牌：ABclonal
型号：A0752
厂商性质： 生产型,服务型,
公司名称： 上海英基生物科技有限公司
吴从杰 : (18611693594) (010-82864773)
（联系我时，请说明是在来宝网上看到的，谢谢！）APAF1 Polyclonal Antibody | A0752_APAF1.pdf | ||||||
Catalog No: A0752 | Species: Rabbit |
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Gene ID: 317 | Isotype: IgG |
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Swiss Prot: O14727 | Purity: Affinity purification |
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Applications: WB IHC ICC | Cross-Reactivity: H M |
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| Size | Price (USD) | Availability |
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| 100ug | ＄300 | Ship in 5 business days | Adding to the cart |
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| 200ug | ＄480 | Ship in 5 business days | Adding to the cart |
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Alt. Names
CED4; APAF-1;
Recommended Dilutions
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC: 1:50-1:100
Products data
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Western blot analysis of extracts of HeLa cell line, using APAF1 antibody. |
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Immunogen
A synthetic peptide of human APAF1
Storage
Store at -20oC or -80oC. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
