乐博现货供应美国ProSci凋亡相关--Caspase-4 (NT) antibody
刘小姐 : (13621283223) (4006130504)
(联系我时,请说明是在来宝网上看到的,谢谢!)刘小姐 : (13621283223) (4006130504)
(联系我时,请说明是在来宝网上看到的,谢谢!)北京乐博生物科技有限公司是美国ProSci授权一级代理商,供应其全线产品涵盖了细胞凋亡、信号传导、肿瘤、免疫、细胞生物、神经生物和传染病等领域。产品应用于ELISA、WB、IHC、FACS等,为您的实验提供多样的检测手段,产品应用文献发表在PNAS、Cell research、Blood……使用广泛。
抗体信息如下:
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1). Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18 (2,3). Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells (4). More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer抯 disease (5).
Caspase-4 (NT), ICH-2, ICE rel II , Mih1
DescriptionLeft: Western blot analysis of caspase-4 in Ramos cells with caspase-4 antibody at (A) 0.5 and (B) 1 μgg/ml.Below: Immunohistochemical staining of mouse spleen using caspase-4 antibody at 2 μg/ml. |
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Caspase-4 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-4.
Affinity chromatography purified via peptide column
This is a polyclonal antibody.
Caspase-4 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Human Casp-4 / ICH-2 / ICE rel II / Mih1 (N-Terminus) Peptide (Cat. No. 3451P)
Casp-4 antibody can be used for the detection of Caspase-4 by Western blot at 1 μg/ml. Depending on cell lines or tissues used, other cleavage products may be observed.
E, WB, IHC
Antibody is supplied in PBS containing 0.02% sodium azide.
Cat. No. 3451P - Casp-4 Peptide
Caspase-4 antibody can be stored at 4?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
H, M
886050
AAA86890
(NT) a caspase induced by ER stress
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