pLP2载体说明书

下载地址：http://www.chem17.com/st178406/Info_105992.html

Zeocin™ belongs to a family of structurally related bleomycin/phleomycin-type 

antibiotics isolated from Streptomyces. Antibiotics in this family are broad 

spectrum antibiotics that act as strong antibacterial and antitumor drugs. They 

show strong toxicity against bacteria, fungi （including yeast）, plants, and 

mammalian cells （Baron et al., 1992; Drocourt et al., 1990; Mulsant et al., 1988; 

Perez et al., 1989）. 

The Zeocin™ resistance protein has been isolated and characterized （Calmels et 

al., 1991; Drocourt et al., 1990）. This protein, the product of the Sh ble gene 

（Streptoalloteichus hindustanus bleomycin gene）, is a 13.7 kDa protein that binds 

Zeocin™ and inhibits its DNA strand cleavage activity. Expression of this protein 

in eukaryotic and prokaryotic hosts confers resistance to Zeocin™.

上海起福生物科技有限公司

联系人：杨建辉

400电话：4006551678

办公电话：021-50724187

传真：021-50724961*8006

手机：15921799099

企业QQ: 4006551678

网址:http://www.qfbio.com/

地址：上海市浦东新区绣川路561号1102室